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The first time my oldest son caught a cold was rough. He was barely four months old, and I was convinced his snotty nose was the start of something serious. I had a thermometer, but no batteries, and my “sick kit” basically amounted to a sample pack of Boogie Wipes from my baby shower.
A reassuring chat with our pediatrician helped ease my worries, but she kindly suggested that I stock up on some essentials for when (not if) this happened again, especially since we were in the thick of cold and flu season.
Fast forward more than a decade and two kids later, and I can honestly say the anxiety that hits when your baby’s congested never fully goes away (I still check to make sure my preteens are breathing at night when they’re stuffed up). However, I’ve learned that having the right tools on hand — beyond a prescription from the doctor! — makes all the difference. Consider this roundup your cold and flu survival kit: it includes all of the sick day essentials I’ve leaned on over the years to get my family through countless fevers, coughs, and late nights.
A Doctor’s Note
I spoke with Biljana Uzelac, M.D., a board-certified pediatrician with more than 20 years of experience and additional training in integrative medicine, about what families should know before stocking their medicine cabinet. Her top recommendations? Have a cool-mist humidifier, a nasal aspirator, and a saline spray ready to go.
She says most mild cold symptoms “can be managed at home with rest, fluids, and comfort measures.” For example, try dressing the baby in lightweight clothing, giving extra snuggles and skin-to-skin contact, and slightly elevating the crib mattress (by placing a rolled towel under it, never inside).
How I Chose What To Put in a Cold and Flu Kit
When putting together this survival kit, I leaned on three key factors:
Expert insights: I consulted pediatric advice from both the American Academy of Pediatrics (AAP) and my interview with Dr. Uzelac, who walked me through what she recommends all families keep stocked at home.
Parent-tested picks: I pulled from my own trial and error after 13 cold and flu seasons, while also tapping into recommendations from the What to Expect Community to see what other parents swear by when their babies are sick.
Selection criteria: Everything included is safe for infants and approved by pediatricians, while also being easy to use and widely available (because when you need it, you can’t wait days for shipping).
In other words, these are the tools I wish I’d had on hand the first time my baby spiked a fever — and the ones I’ll never go without again.
Why Trust Us?
What to Expect is the world’s most trusted pregnancy and parenting brand for a reason. Our product recommendations are based on expert parent insight, advice from medical professionals and feedback from the millions of parents and parents-to-be in our community. Our editors adhere to the highest research and reporting standards and our team of vetted OB/GYNs, pediatricians and other health professionals ensure our recommended products are safe and effective for you and your baby.
When it comes to sick babies, accuracy is everything. This rectal thermometer was chosen as WTE’s best baby thermometer for precisely that reason. The AAP considers rectal thermometers the gold standard for infants, and FridaBaby’s version makes the process less intimidating.
The flexible tip and parent-friendly grip help you get a quick, accurate read in just 10 seconds. Plus, the backlit display means even middle-of-the-night checks are easy without turning on a light.
Just like several WTE community parents, I preferred using Little Remedies Spray and Drops because it gave me the option of squeezing a couple of drops into a nostril instead of startling an already-fussy baby with a big spray up the nose. Either way you do it, this gentle saline spray moisturizes nasal passages and loosens mucus without any medication, so it’s perfect for even the tiniest babies. I always applied it before using the nasal aspirator to help get stubborn congestion moving, and it made a huge difference.
“I used the little remedies spray nightly with my little guy to help flush down anything from his reflux, his dr told me to. I use it as a dropper instead of a spray, I just drop a couple drops in each side, he doesn’t like it but I know it makes him feel better, I let it sit like a minute or two, then I use the nose Frida to get anything out.”
“I use the drops when he’s on his changing pad. Laying flat. I just insert the dropper (it doesn’t go deep, maybe .25cm) and squeeze 1 tiny drop per nostril and just let it roll into his nose. We use little remedies infant and our LO has no issues with it - as in he doesn’t freak out over the drops in his nose.”
Recommended ages: Safe for infants and older babies
Why We Love it
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Why We Love It
You probably got a bulb syringe at the hospital when your baby was born, and while that works fine for clearing small amounts of snot, there’s truly no comparison to the suction power you get with theNoseFrida.
It tackles even the stuffiest noses using parent-generated suction (not as gross as it sounds — there’s a hygienic filter). With overwhelmingly positive feedback from parents and a tried-and-true design, it’s hands-down the best nasal aspirator for babies.
“Baby girl had a bad cold a couple weeks ago, and we were sucking snot multiple times a day! It took a minute to get the hang of it, and now I find it oddly satisfying to get a good suck”
“This thing is a lifesaver!! I’ve been using it since my son was about a month or so… he will be 6 months tomorrow. I love it so much I have bought for all my mom to be friends! BTW, his pediatrician is who recommended it to us.”
I used the nose Frida for my son 11 years ago, it was the ONLY thing powerful enough to actually clear him and he didn’t scream and cry. So it’s been my staple for baby shower gifts and they always look at me like I’m crazy and they’ll never do it. Then I typically get texts thanking me later. Nose Frida is a must!
“The Frida one works best honestly. The one that you have to manually suck with your mouth. I have an electric one too and the Frida one works great. Definitely saline first and it loosens it to come right now.”
The best baby humidifier is one that’s easy to clean and uses cool mist. A 2025 Sleep Awards winner, this 3-in-1 Vicks version (I bought it not too long ago to replace an old one, and it's an absolute workhorse!) checks all the boxes and then some.
It features a filterless design that’s simple to sanitize and a whisper-quiet motor that won’t wake your baby. It’s also a night light (cycle between seven different colors) and even provides cough and congestion relief as a vaporizer.
“I like the Vicks because it’s cool mist and you can add the Vicks vapor things too it. When my youngest is congested it’s so nice to have that running. I’d probably get another one if this one breaks. I do wish there was something a little smaller but the size keeps me from having to fill it too often.”
“I have been through a few humidifiers! My toddler has the Vicks filter free cool mist ultrasonic one in his room and I love it- it’s pretty easy to clean, holds a lot of water and has different settings that really let you humidify a lot of different size rooms.”
Quantity: 1.5-ounce jar Recommended ages: 2 months+
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Why We Love It
For little ones too young for medicated rubs, this gentle balm is a lifesaver. Made with eucalyptus, lavender, and beeswax, it helps soothe congestion without any potentially harsh ingredients.
It was a bedtime staple when my kids were congested — and it’s still part of our comfort ritual today because it smells incredible. Like several WTE community members, I’ve seen success applying this to my sons’ feet to help ease congestion.
As mentioned above, Boogie Wipes were one of the few sick-baby essentials I actually had on hand the first time my oldest got sick — and I’m so grateful I did. Raw, chapped noses from dry tissues are no fun for babies (or parents).
These saline-infused wipes gently dissolve dried boogies without stinging or irritation. They’re perfect for clearing clogs before using an aspirator. I always reached for the unscented version since my little ones have sensitive skin — and they worked like a charm.
“After some particularly bad allergy seasons this year, I found the boogie wipes really did work best for crusty noses. The saline really helped quickly break up the snot”
Aquaphoris one of those do-it-all staples every parent should have. From red noses to chapped cheeks, this ointment forms a protective barrier that helps irritated skin heal.
It’s especially great for preventing rashes from runny noses and frequent wiping. I kept the baby-specific version in nearly every room during cold and flu season — it’s that useful. And yes, I still use it for all sorts of things even now that my kids are older.
When your baby is sick, comfort is everything. The Little Sleepies Zippy is a buttery-soft bamboo viscose sleeper that’s naturally temperature-regulating — perfect year-round, even when your little one is feverish.
It’s lightweight, machine washable, and built to last thanks to the stretchy flip-footed design that grows with your baby. Fold-over mittens help keep them from scratching at their stuffy nose, and the footies make it easy to try the chest-rub-on-feet trick without wrestling on socks.
“They last so long! My 2.5 year old can still wear her size 6-12 month zippies. She is small and the feet covers don’t fit anymore so now they are like a romper. I love them! They are a thinner material though so I hang them dry and do a bamboo load all together.”
“I love them! The material is stretchy so you can reuse for a long time. My son has three sets, just ordered one of the latest Nemo ones too. They have little parts you can fold over to cover feet and hands or leave uncovered. The material is a little light, but still great for summer and spring. I would recommend!”
“Little sleepies last a really long time. My baby can still fit (but probably only for 1-2 more weeks) in his premie size from birth (4 months on Friday). My baby was NOT a premie, born at 6lb 11oz. The sizes run a bit larger and they are super stretchy.”
“Little Sleepies are my favorite! I’ve tried a few different brands: Magnetic Me, Posh Peanut, Kickee, Larkspur. Little Sleepies Zippies have the most stretch of those brands. I like the fold over footies so if the babe is longer the feet can stick out. My son is 75th percentile in length and can still wear his 0-3 month size LS. Other brands he’s in the next size.”
If your doctor prescribes medication — or you’re giving a baby-safe OTC pain reliever (Infants' Tylenol is a resounding favorite!) — getting it down can feel like an Olympic event. The MediFrida Accu-Dose Paci makes it easier by delivering medicine through a pacifier design that bypasses taste buds and reduces spit-up.
When parents in the WTE community asked for medicine-giving hacks, this gadget came up more than any other. It wasn’t around when my boys were babies, but I really wish it had been.
“My baby also threw up the first time I tried giving her medicine after her shots. What worked for us is to use pacifier with the medicine dispenser in it and now it’s the only way she takes medicine even though she doesn’t take a paci”
“My little guy had to take amoxicillin too and he didn’t like the syringe. We got the Frida Baby Medi Frida the Accu-Dose Pacifier Baby Medicine Dispenser from Amazon and it worked much better than the syringe.”
Many parents instinctively reach for OTC cold and cough medicines, but Dr. Uzelac notes that “most are not recommended for children under 6.” Instead, she often turns to gentler measures — often homeopathy.
“Homeopathy has a low risk of side effects and won’t mask symptoms, so it can be a great place to start,” she says. She recommends ColdCalm Baby for nasal congestion because it’s suitable for little ones as young as 6 months. These single-dose liquid vials target common cold symptoms like runny noses and congestion, and parents in the WTE Community swear by them during sick season.
“Ugh, colds at this age are so tough. My little one just got over a cold, and it was terrible because she would scream bloody murder if I tried to suck any of it out. She wouldn’t let me. I purchased a homeopathic medicine (natural) for colds for little ones, and it helped her SO much! It’s called ColdCalm Baby, and it comes in pre-measured doses. You can give up to 6 times a day, I believe. It was a lifesaver for us.”
“Was coming here to second ColdCalm !! It’s literally my life saver - I basically give it to my daughter as a preventative now too! It’s soooo helpful.”
Always check with your doctor before giving your baby any fever-reducing medication. The AAP says infant acetaminophen can help reduce a fever (WTE parents prefer Infants' Tylenol), and ibuprofen may be used for babies over 6 months. You can also apply a cool compress or give a lukewarm bath to help bring their temperature down.
Are there any essential oils that are good for a sick baby?
Check with your pediatrician first. Using essential oils directly on babies under 2 is generally not recommended — their skin and airways are too sensitive, and oils can cause irritation or breathing issues if misused. However, some baby-safe products (like the chest rub above) use diluted essential oils to aid congestion or sleep.
When should I call a doctor?
Most colds clear up within 7 to 10 days, according to Dr. Uzelac, but you should call your pediatrician if your baby has a fever that lasts longer than three days, a fever above 102°F in older infants and children, or any signs of dehydration (fewer wet diapers, dark urine, no tears when crying).
For babies under 2 months, any temperature of 100.4°F or higher is an emergency and requires an ER visit. Other red flags include trouble breathing, wheezing, persistent ear or sinus pain, bluish lips or face, seizures, or behavior that feels “off.”
“You know your child best,” Dr. Uzelac adds, “so if something is out of the ordinary, seek help.”